Search on: GENES, METASTASIS SUPPRESSOR 
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Descriptor English:   Genes, Tumor Suppressor 
Descriptor Spanish:   Genes Supresores de Tumor 
Descriptor Portuguese:   Genes Supressores de Tumor 
Synonyms English:   Antioncogenes
Cancer Suppressor Genes
Emerogenes
Genes, Cancer Suppressor
Genes, Growth Suppressor
Genes, Metastasis Suppressor
Growth Suppressor Genes
Metastasis Suppressor Genes
Tumor Suppressor Genes  
Tree Number:   G05.360.340.024.340.375.249
G05.360.340.024.340.415.400
Definition English:   Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible. 
Indexing Annotation English:   Manual 24.4.4.3
See Related English:   Tumor Suppressor Proteins
 
History Note English:   2002 (1991) 
Allowable Qualifiers English:  
DE drug effects ES ethics
PH physiology RE radiation effects
Record Number:   28963 
Unique Identifier:   D016147 

Occurrence in VHL:
 

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